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Hypothyroidism (Underactive Thyroid): Symptoms, and Treatment

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Hypothyroidism (underactive thyroid)

Understanding Hypothyroidism (Underactive Thyroid)

Hypothyroidism, commonly referred to as an underactive thyroid, is a condition where the thyroid gland fails to produce sufficient thyroid hormones. These hormones play a critical role in regulating the body’s metabolism, affecting energy levels, temperature regulation, and even heart function. When the thyroid gland underproduces hormones, various bodily functions slow down, leading to a variety of symptoms. Hypothyroidism is a manageable condition when diagnosed and treated appropriately.

Symptoms of Hypothyroidism

The symptoms of hypothyroidism can vary depending on the severity of hormone deficiency. They often develop gradually and may be mistakenly attributed to aging or other conditions. Common symptoms include:

  • Fatigue
  • Weight gain
  • Sensitivity to cold
  • Dry skin
  • Constipation
  • Depression
  • Muscle weakness
  • Slow heart rate
  • Memory problems
  • Heavy or irregular menstrual cycles

Severe untreated cases of hypothyroidism can result in a life-threatening condition known as myxedema coma.

Causes of Hypothyroidism (Underactive Thyroid)

There are several causes of hypothyroidism, with autoimmune conditions being the most common. Hashimoto’s thyroiditis, an autoimmune disorder, leads to the destruction of thyroid tissue, impairing hormone production. Other causes include:

  • Iodine deficiency: Essential for thyroid hormone production, iodine deficiency can lead to thyroid dysfunction, though rare in developed countries due to iodine-enriched diets.
  • Thyroid surgery or radiation therapy: Surgical removal or radiation therapy for hyperthyroidism or cancer can result in hypothyroidism.
  • Medications: Certain drugs, such as lithium, can interfere with thyroid function.
  • Congenital hypothyroidism: Some infants are born with underdeveloped thyroid glands, requiring early diagnosis and treatment to prevent developmental delays.

Diagnosing Hypothyroidism (Underactive Thyroid)

Diagnosing hypothyroidism primarily involves blood tests to measure thyroid hormone levels. A thyroid-stimulating hormone (TSH) test is commonly used to determine whether the thyroid is functioning properly. If TSH levels are high and thyroxine (T4) levels are low, it indicates hypothyroidism. In some cases, additional tests, such as testing for thyroid antibodies, may be used to confirm autoimmune-related hypothyroidism.

Treatment Options for Hypothyroidism

The standard treatment for hypothyroidism involves thyroid hormone replacement therapy, usually with a synthetic form of thyroxine known as levothyroxine. Levothyroxine is a safe and effective treatment when administered in the correct dosage. It is important to monitor thyroid hormone levels regularly to adjust medication as needed. This treatment can restore normal hormone levels and alleviate symptoms.

Patients typically take levothyroxine daily, and it may take several weeks before improvements in symptoms are noticeable. Long-term management with regular blood tests is necessary to ensure thyroid hormone levels remain stable.

Complications of Untreated Hypothyroidism

If left untreated, hypothyroidism can lead to several complications. For instance, it can cause high cholesterol, increasing the risk of heart disease. Severe untreated cases can lead to myxedema coma, a rare but life-threatening condition. Hypothyroidism during pregnancy can also harm both mother and child, leading to developmental delays if not properly managed.

Conclusion

Hypothyroidism (underactive thyroid) is a common and manageable condition with appropriate treatment. Early diagnosis and proper management with hormone replacement therapy can prevent serious complications. It’s important to monitor symptoms and seek medical attention if any signs of hypothyroidism appear.


Source


Epidemiology, Types, Causes, Clinical Presentation, Diagnosis, and Treatment of Hypothyroidism:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613832

Hypothyroidism in the older people: diagnosis and management:

https://www.tandfonline.com/doi/full/10.2147/CIA.S23966


Evaluation of New Measures of the Impact of Hypothyroidism on Quality of Life and Symptoms: The ThyDQoL and ThySRQ:

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1524-4733.2007.00232.x


Subclinical Thyroid Disease:

https://www.aafp.org/pubs/afp/issues/2005/1015/p1517.html

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